Accurate Calculations of Auger Cascade for Medical and Physical Applications

Auger electrons and characteristic X-rays, collectively named as atomic radiation, are emitted following atomic ionization. Radioisotopes that emit Auger electrons have been of particular interest as therapeutic agents. This is primarily due to its short range in tissue, controlled linear paths and high linear energy transfer of these particles. Their biological effect is very localised thus making nuclear targeted Auger-electron emitters ideal for precise targeting of cancer cells. Accurate knowledge of Auger yields is needed both to evaluate the dose to healthy cells when radioisotopes are administered for diagnostics, and to design radioisotope use in the targeted cancer therapy.